Skin Supplements / Skin Boosters / Subcutaneous IV Drip[Extracted from Salmon] Endran Healer
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[Extracted from Salmon] Endran Healer
Endran Healer is a procedure that injects polynucleotide (PN) ingredients, derived from salmon, into the skin. This helps to alleviate dryness within the skin and improve the overall skin environment, leading to enhanced elasticity and the maintenance of healthy skin. *VAT separate
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Distinctive Features of PN Booster Treatment
1. Same Ingredient Composition, Affordable Cost
It is the same as the core ingredient of the widely known salmon injection.
The core ingredient, PN, is included in the same concentration, offering similar expected effects while reducing the cost burden.
2. Not a Simple Injection, but a Precisely Planned Procedure
By considering the skin structure and injecting the PN ingredient into the precise layer and depth, treatment efficacy can be enhanced.
3. Accuracy Verification Through Observation of Papule Formation
Immediately after the procedure, we check the papule formation on the skin with the patient to ensure that the PN ingredient has been precisely injected into the target area.
4. Consultation and Procedure Performed Directly by the Director
After carefully diagnosing the patient's skin condition and past treatment history, we establish and proceed with a customized treatment plan for each individual.
5. Minimizing Skin Irritation and Concluding with Recovery in Mind
We use a Jaungo modeling pack to help even sensitive skin soothe comfortably and reduce the burden of recovery.
6. Adjustment of Papule Interval per Treatment Area
For areas like the cheeks or forehead, the injections are spaced considering the desired effect, while sensitive areas like around the eyes or mouth are treated more densely. This is determined by closely assessing skin thickness, elasticity, and wrinkle direction. Even with the same dosage, the procedure is customized for each area.
PN Booster Treatment, Why Consider It?
1. Same Ingredients, an Alternative for a Smart Choice
The patent period for PN (Polynucleotide), the main ingredient in the widely known salmon injection, has expired, and various products based on the same salmon-derived PN are now being released.
Our clinic's PN Booster also contains the same ingredients, and
helps you receive treatment at a relatively affordable cost.
We offer a realistic PN treatment that maintains the expected effects while reducing the price burden.
If you are considering a cost-effective PN injection, our clinic's PN Booster could be an option.
2. Injection Method More Important Than the Ingredient Itself
It is difficult to expect identical results simply because PN ingredients are included.
Our clinic's PN Booster treatment does not simply mean a mere injection process.
We carefully calculate and inject into the precise skin layer, appropriate depth, and necessary dosage.
Considering each patient's skin thickness, degree of damage, and pore structure, the procedure is adjusted to the appropriate depth for each skin layer.
Only with this approach can true dermal remodeling and collagen regeneration be expected.
3. We confirm the injection site through papule formation.
At our clinic, whether the PN ingredient has been accurately injected into the skin
is visually confirmed by both the medical staff and the patient.
Papule formation can be an indicator that the medication has appropriately reached the target area, rather than simply being a side effect.
Therefore, we have a procedure to confirm papule formation with the patient after the treatment.
A brief confirmation of papule formation can positively influence satisfaction with the treatment results.
4. 1:1 Customized Consultation and Treatment Performed Directly by the Director
Rather than a typical explanation handled by a consultation manager, the director directly prioritizes communication with the patient.
The patient's skin condition, sensitivity, and past treatment history, as well as any cosmetics or medications currently in use,
the director directly and meticulously assesses and confirms throughout the entire procedure.
Through this process, we help the PN ingredient work more effectively.
At the same time, we strive to reduce unnecessary inflammation or the risk of side effects.
5. Minimizing Irritation and Aiming for Rapid Recovery
After PN treatment, we include Jawoongo modeling pack application as a basic step.
We provide herbal complex soothing care that quickly calms heat, redness, and sensitive reactions that may appear after the procedure.
This can help to soothe the skin in advance before excessive immune responses occur.
Through this process, even those with thin or sensitive skin can comfortably receive PN treatment.
We strive to provide integrated care that considers not only the treatment process but also skin recovery.
6. Customized Embo Spacing Design per Area
During PN Booster treatment, we carefully plan not only the injection areas but also the injection intervals.
For example, for areas like the cheeks or forehead, where the dermis layer is relatively thick and wide,
the PN component can diffuse widely from a single point, so good results can be expected even with intervals of about 1~1.5cm.
Conversely, for areas with thin skin and many fine wrinkles, such as around the eyes or mouth,
we inject more delicately at 0.5cm intervals to help improve skin texture.
If the skin is generally thin or there are many sunken areas,
or if the skin texture structure has become irregular due to laser treatments, we consider injecting more densely even in the cheek or forehead areas.
Considering skin thickness, elasticity, wrinkle direction, and treatment goals comprehensively,
we plan the treatment with personalized embossing positions and intervals.
Even when using the same amount of PN, different treatment methods can lead to different results.
Providing personalized, non-mechanical treatment that considers each individual's skin condition is an important characteristic of PN Booster treatment.
What effects can you expect from PN Booster treatment?
1. It can induce collagen and elastin production, leading to thicker and more elastic skin.
PN (polynucleotide) components derived from salmon stimulate fibroblasts in the skin's dermis layer,
promoting the production of collagen and elastin.
→ This leads to an increase in skin thickness, helps alleviate fine wrinkles and restore elasticity,
and you can also expect pore improvement effects.
2. Contributes to the recovery of damaged skin barriers and strengthens self-regeneration.
PN promotes the secretion of growth factors like TGF and FGF, aiding epidermal cell regeneration and contributing to skin barrier recovery.
→ This can have a positive impact on improving inner dryness, alleviating sensitivity, and enhancing the skin's natural regenerative power.
In particular, it can help accelerate the recovery process of sensitized skin after laser or peeling treatments.
3. Naturally Improving Skin Changes
PN Booster is not a treatment that adds volume to the skin like fillers or paralyzes specific muscles like Botox.
→ Instead, it helps enhance the skin's natural regenerative power, leading to smoother skin texture, alleviating inner dryness, and improving makeup adherence.
If you seek more natural skin improvement and health, you may consider PN Booster treatment.
Principle of PN Booster Action
1. Inducing Skin Structure Improvement through Fibroblast Activation
The PN (polynucleotide) component used in PN Booster
consists of high-purity DNA fragments extracted from salmon. When this component is injected into the skin,
it acts similarly to a skin damage signal, inducing the activation of fibroblasts.
Activated fibroblasts produce skin-constituting substances such as collagen, elastin, and hyaluronic acid,
contributing to improved skin thickness and elasticity, and creating a healthy skin structure.
2. Restoring Skin Regenerative Power through Growth Factor Secretion Promotion
Activated fibroblasts play a role in secreting various growth factors related to skin regeneration.
TGF-β factors help in collagen synthesis.
FGF plays a role in promoting skin regeneration and recovery.
VEGF contributes to improving microvascular circulation in the skin.
These growth factors create an environment where the skin can regenerate itself.
As a result, they help the epidermis and skin barrier recover naturally.
Through this process, skin sensitivity can be reduced, inner dryness can be alleviated, and overall resilience can be enhanced.
3. You may feel your skin is filled in due to improved dermal density.
Ggeuthan Clinic PN Booster primarily acts on the dermis layer, a crucial part of the skin.
The PN component helps in the remodeling of the ECM (extracellular matrix), a major constituent of the dermal layer.
It encourages the dermal tissue to be filled more densely with collagen, hyaluronic acid, and various proteins.
This leads to improved elasticity and volume within the skin. Skin texture can also be refined, leading to an effect where makeup blends in better.
4. Reduces skin irritation, promotes rapid recovery, and aids in anti-inflammatory action.
The PN component not only helps in skin regeneration but also plays a role in regulating subtle inflammatory responses within the skin.
Chronic redness
Skin sensitive to external stimuli
Sensitive reactions occurring after laser treatments
In such cases, it can help alleviate the skin's inflammatory response and induce a healthy recovery process.
Thanks to these characteristics, Ggeuthan Clinic PN Booster is known as a PN treatment that can be considered even for relatively sensitive skin.
Ggeuthan Clinic PN Booster Treatment Procedure
1. Skin Condition Analysis and Diagnosis
By thoroughly understanding the patient's skin thickness, elasticity, and sensitivity,
the depth and method of PN injection are carefully determined.
2. Individual Consultation with the Director
The areas requiring skin improvement and the treatment zones are
personally examined by the director, who then develops a treatment plan.
A customized treatment plan is established, considering each individual's skin characteristics.
3. Anesthetic Cream Application
As this treatment directly delivers the PN component to the dermal layer,
a sufficient numbing time of 20 to 30 minutes is allowed
to reduce discomfort that may occur during the procedure.
4. Ggeuthan Clinic PN Booster Full Treatment
The PN component is precisely injected into the pre-planned depth and target locations.
The position of the injected PN is immediately confirmed through the 'embossing effect',
and if necessary, fine adjustments are made instantly to enhance the accuracy of the procedure.
5. Soothing Treatment using Jaurungo Modeling Pack
Immediately after the procedure, a Jaurungo modeling pack is used to
rapidly calm needle marks, erythema, and heat sensation.
This prevents excessive immune responses and helps the skin recovery process conclude comfortably.
Ggeuthan Clinic PN Booster Recommended Treatment Cycle and Duration
1. Intensive Initial Treatment (typically 3 sessions)
To achieve the full benefits of PN components, a series of about three treatment sessions, typically spaced one month apart, is generally recommended.
This is because the PN components require time to sufficiently reach and accumulate in the skin's dermis layer.
During this process, fibroblasts within the skin can be activated.
This helps promote consistent collagen remodeling.
As a result, it contributes to a stable skin regeneration process.
2. Maintenance Treatments
To maintain the improved results for a longer period,
maintenance treatments can be considered approximately once every 6 months to a year.
The duration of treatment effects can vary depending on your individual skin condition and lifestyle habits.
Generally, after the recommended three treatment sessions, the effects can be maintained for approximately 6 to 12 months.
3. How long do the effects last?
Once the collagen remodeling process is complete,
improvements in skin texture, elasticity, and density can be expected to last for an average of 6 months or more.
However, in certain situations, the duration of these effects might be shorter.
If your skin is naturally very thin or highly damaged,
if you have lifestyle habits that negatively impact skin health, such as smoking or excessive UV exposure, the duration may differ.
4. When can you expect to feel the effects after treatment?
Immediately after the treatment, you may temporarily experience some 'embossing' (small raised bumps) or mild swelling.
After about 1 week, you may notice that makeup applies more smoothly and your skin texture begins to improve.
By weeks 2 to 3, you can expect improved skin elasticity, increased density, and a softening of fine lines.
After completing all three treatment sessions, you will likely experience a more noticeable improvement in your overall skin condition as the internal skin structure changes.
What level of pain can I expect during a PN Booster treatment?
The pain experienced during the treatment can be described as a tolerable stinging sensation.
Since PN components are injected into the skin's dermis layer, it is not entirely painless.
However, we apply sufficient anesthesia before the treatment, so most patients find the procedure comfortable.
Differences in Pain by Area
You may experience little to no pain around the cheeks, forehead, and mouth.
A momentary stinging sensation may be felt around the eyes, bridge of the nose, and chin.
In areas with larger pores, you might feel a dull, pressing sensation.
Methods to Reduce Pain During Treatment
We ensure sufficient time for the anesthetic cream to take full effect.
During the treatment, we inject the components slowly and in small amounts to minimize irritation.
We monitor your pain level in real-time during the treatment.
After the treatment, we apply a calming pack to soothe your skin and ensure a comfortable finish.
When to Consider PN Booster
1. Individuals with a noticeable increase in fine lines
It can be particularly helpful for those with a dense network of fine lines around the eyes, sides of the cheeks, and mouth.
It may be suitable for those who find lifting or filler treatments daunting but desire natural wrinkle improvement.
2. Individuals whose skin has become sensitive and frequently reddens
Individuals with sensitive skin that reacts easily to changes in cosmetics or frequently experiences flushing may also consider it.
For those who want to restore a weakened skin barrier to health
Also suitable for those whose makeup often flakes due to inner dryness.
This is for when you are concerned about a skin condition where your skin feels dry and tight underneath, even if it's oily on the surface, and makeup flakes.
Suitable for dehydrated skin with persistent inner tightness despite sufficient moisturizing.
Suitable for those whose skin has become sensitive and fatigued due to frequent treatments.
Used to aid recovery when skin has become thinner or more sensitive due to treatments such as laser or peeling.
Recommended when you want to improve overall skin condition and boost its fundamental strength.
Can be considered when you want to improve skin density and surface texture.
Helpful in cases where skin elasticity has decreased, giving an overall loose and saggy appearance.
May be suitable for those whose elasticity in the cheekbones or cheeks appears reduced, and whose skin texture is uneven and unrefined.
Embossing Reaction After PN Booster Treatment
After PN Booster treatment, small, raised, convex shapes like embossing may temporarily appear on the skin.
This embossing can be interpreted as a positive sign that the medication has been well delivered to the dermal layer of the skin.
The phenomenon of the skin rising in small bumps is a natural reaction, and you can have positive expectations for the treatment's effect.
Generally, the embossing naturally disappears within 1-2 days.
For those with thin or dry skin, it may last about 2-3 days, and in sensitive areas like around the eyes or mouth, it may persist for up to 4 days.
Rarely, the embossing may persist for 5-7 days or more, however,
you do not need to worry much if it is not accompanied by unusual pain, heat, or excessive redness.
This can also be seen as a positive outcome, as the medication is slowly absorbed and acts on the skin for a longer period.
Precautions After Treatment
- ✔ Minor bumps, redness, and slight discomfort in the treated area may appear for about 2-3 days.
- ✔ Small bruises or needle marks, and mild swelling may persist for about 1-2 weeks after the treatment.
- ✔ To minimize irritation to the treated area, it is recommended to avoid alcohol, smoking, saunas, swimming pools, and strenuous exercise for at least 7 days.
- ✔ After treatment, please pay special attention to skin soothing and moisturizing care, and it is important to apply sunscreen thoroughly when going out.
Q&A
고객님들이 가장 많이 물어보시는 내용을 모았습니다.
Is it similar to Rejuran treatment?
Endran Healer contains the same polynucleotide (PN) ingredient as Rejuran. It can especially help alleviate dryness within the skin and have a positive impact on creating a healthy skin environment.
What is the appropriate treatment cycle?
Generally, we recommend receiving a total of 3 treatments at one-month intervals.
Is manual injection the only method available?
If you are sensitive to pain, you can also choose a treatment using Dermashine equipment.



